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Senior Knowledge Engineer, Ontology and Data Standards (Contract)

Altos Labs · San Francisco Bay Area, CA · On-site

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About Altos Labs

Altos Labs is a biotechnology company focused on restoring cell health and resilience through cell rejuvenation to reverse disease, injury, and the disabilities that occur throughout life. Learn more about Altos. Backed by General Catalyst.

About the role

Design, maintain, and extend internal LinkML / Biolink models and ontologies covering experimental and prior-knowledge metadata—driven by competency questions from user requirements and not by source-side convenience. Administer, steer, and refine our agentic curation framework and Model Context Protocol (MCP) service layer to scale data profiling, validation, and entity mapping far beyond manual capacity. Found on 1752vc Careers, the job board for startup and VC roles.

What they're looking for

  • Biological Data Lifecycle: Direct experience turning messy, real-world exploratory datasets (genomics, single-cell, screening, imaging) into structured metadata
  • Software & Data Management: Familiarity with Git, GitHub Actions, graph/relational databases, and cloud storage (e.g., AWS S3)
More about this role

Our mission is to restore cell health and resilience through cell rejuvenation to reverse disease, injury, and the disabilities that can occur throughout life.

For more information, see our website at altoslabs.com.

Our Single Altos Value: Everyone Owns Achieving Our Inspiring Mission .

Altos Labs has been named one of the Top 3 Biotech Companies and ranked for the second year on the Forbes 2026 Best Startups in America list. At Altos, exceptional scientists and industry leaders from around the world work together to advance a shared mission. Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives. We are all accountable for sustaining a diverse and inclusive environment.

  • As a contract Senior Knowledge Engineer, Ontology and Data Standards, you will drive how our team represents biological knowledge At Altos
  • We have built the machinery: a large canonical LinkML/Biolink schema including REST/MCP/CLI service layer; specification packages covering multiple prior-knowledge sources; and an agentic / human-in-the-loop curation framework. What it lacks is a technical owner—someone to govern and administer the content.
  • You...

Read the full posting on Altos Labs's site ↗

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