Learn about how ARTBIO is redefining cancer care through a new class of alpha radioligand therapies and building an ecosystem to maximize their potential. Backed by Third Rock Ventures.
About the role
Develop clinical imaging and dosimetry strategies designed to support clinical development plans for ARTBIO's RLT agents. Design and implement imaging protocols, plans and procedures for clinical studies.
What they're looking for
- Minimum 5 years of relevant industry experience for appointment at Associate Director, 8 or more years for appointment at Director
- Direct experience designing and managing imaging aspects of clinical protocols for oncology radiopharmaceutical agents, including study design, endpoint selection, dosimetry, harmonisation between clinical sites and imaging core lab oversight
- Specific experience with imaging study design and direct or indirect estimation of normal organ and tumour dosimetry for early-stage clinical development of RLT agents
- Demonstrated expertise in quantitative SPECT/CT and PET/CT in a clinical setting
- Working knowledge of internal dosimetry principles
- Experience authoring imaging charters and site imaging manuals to regulatory standards
More about this role
Summary
We are seeking an Associate Director / Director of Clinical Imaging who will be expected to take on a highly visible role with internal and external stakeholders through development of the strategy and management of imaging and dosimetry for clinical protocols in ARTBIO's Radioligand Therapy (RLT) clinical development programs. As a critical member of the Clinical Team, you will work closely with program leads, functional heads and subject matter experts to advance the company's development pipeline.
Imaging and dosimetry strategy
Develop clinical imaging and dosimetry strategies designed to support clinical development plans for ARTBIO's RLT agents.
Design and implement imaging protocols, plans and procedures for clinical studies.
Define quantitative imaging standards across the portfolio, including acquisition and reconstruction parameters, calibration and QC frameworks, and site qualification criteria for SPECT/CT and PET/CT.
Oversight of dosimetry methodology: segmentation and registration, time-activity curve fitting, time-integrated activity estimation, and organ- and lesion-level absorbed dose calculation.
Evaluate and integrate emerging imaging methods, including...
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