Denali Therapeutics brings the power of biotherapeutics to the whole body, including the brain. We discover, develop and deliver medicines for people living with serious diseases. Backed by GV.
About the role
Provides medical oversight of clinical trial design, ensuring scientific rigor, endpoint defensibility, and alignment with regulatory expectations Establishes clinical development standards, frameworks, and best practices across programs.
What they're looking for
- Required
- M.D. or M.D./Ph.D. with formal training in the areas of neurology, neuroscience, genetics, immunology, and/or rare disease
- Minimum 12 years of combined experience, with at least 7 years in the pharmaceutical or biotechnology industry in senior medical/clinical roles
- Typically 3 or more years in a people management role, with demonstrated success in talent development, performance management, and team building
- Deep expertise in clinical trial design, endpoint strategy, SAP development, regulatory interactions, and DSMB/IDMC processes
- Proven experience leading or contributing significantly to a pivotal trial data readout, including topline analysis, NDA/BLA regulatory submission, and external data disclosure
More about this role
Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients.
We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.
Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegeneration and other serious medical conditions. Denali has engineered the TransportVehicle (TV) platform enabling the delivery of enzymes, oligonucleotides and antibodies that cross the blood brain barrier and provide enhanced peripheral distribution. Biotherapeutics in the TV platform have the potential to unlock treatment for serious diseases that are not available through traditional approaches.
The Executive...
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