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Senior Scientist, LNP, Process Development & Manufacturing

ElevateBio · Waltham, Massachusetts, United States · On-site

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About ElevateBio

ElevateBio is powering the industry with an integrated approach to technologies and manufacturing. Backed by SoftBank VF.

About the role

We are seeking a highly skilled LNP Senior Scientist to join our process development team at ElevateBio. The ideal candidate will have hands-on experience in LNP formulation, targeted LNP (tLNP) engineering through bioconjugation, and a complete understanding of LNP-based processes. As an LNP Scientist, you will be responsible for designing and executing LNP formulation studies while also working closely with cross-functional teams and external clients for the manufacturing of LNP-based therapeutics.

What they're looking for

  • Familiarity with GMP regulations, regulatory expectations, and preparation of technical documentation supporting CMC activities, technology transfer, and regulatory filings for LNP-based formulated products
  • Proven record of manufacturing LNP-based products through either process development work or tech transfer activities
  • Ability to analyze and interpret data linking receptor engagement, ligand density, nanoparticle properties, cellular uptake, and delivery performance to guide tLNP optimization
  • Experience operating automated LNP manufacturing and process development systems (e.g., PNI/Cytiva, Knauer) and filtration systems, including tangential flow filtration (TFF) platforms (e.g., Repligen)
  • Ability to analyze complex experimental data, troubleshoot process challenges, and collaborate cross-functionally with MSAT, analytical development, manufacturing, and external partners
More about this role

ElevateBio is a technology-driven company powering the industry forward by helping partners realize the potential of their therapies from design to commercialization. We have integrated a differentiated set of technologies, end-to-end services, and industry-leading manufacturing expertise to develop advanced therapies faster and more efficiently.

We are seeking a highly skilled LNP Senior Scientist to join our process development team at ElevateBio. The ideal candidate will have hands-on experience in LNP formulation, targeted LNP (tLNP) engineering through bioconjugation, and a complete understanding of LNP-based processes. As an LNP Scientist, you will be responsible for designing and executing LNP formulation studies while also working closely with cross-functional teams and external clients for the manufacturing of LNP-based therapeutics. Your work will be critical in advancing the translation of LNP therapeutics from development through large-scale manufacturing at ElevateBio.

  • Lead the execution for LNP formulation studies to support process characterization, technology transfer, and manufacturing readiness for LNP-based drug products.
  • Work closely with cross-functional...

Read the full posting on ElevateBio's site ↗

Process Development

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