ESM3. Enabling scientists to understand, imagine, and create proteins. Backed by Lux.
About the role
Biohub operates one of the largest AI compute clusters dedicated to biology, spanning three frontier research institutes with some of the world's leading biologists. We're not a startup trying to find product-market fit, and we're not a pharma company optimizing a pipeline. We're building frontier AI for fundamental science, as open science, at a scale no one else is doing. This is a unique moment for scientific acceleration.
What they're looking for
- Build on and advance the AI systems at the frontier of biology to accelerate science
- Design novel model architectures and scale pre-training pipelines for our biology foundation models
- Build post-training systems that drive biological discovery: RL, reward modeling, reasoning, and multi-agent orchestration for long-horizon scientific tasks
- Design evaluation frameworks and AI systems with scientists across Biohub and beyond, grounded in real biological outcomes and real world impact
- Engage the wider scientific community through impactful publications, open-source releases, and collaborations worldwide
More about this role
Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.
Biohub operates one of the largest AI compute clusters dedicated to biology, spanning three frontier research institutes with some of the world's leading biologists. We're not a startup trying to find product-market fit, and we're not a pharma company optimizing a pipeline. We're building frontier AI for fundamental science, as open science, at a scale no one else is doing. This is a unique moment for scientific acceleration. The problems are among the hardest and most impactful problems you can choose to work on, and we move at a pace that meets this moment.
- Frontier molecular modeling, from protein language models (e.g., ESM) to structure prediction (e.g., ESMFold) and beyond.
- Scaled biological foundation...
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