Startups · AI

Scientist II, Scaling Lead

Evolutionary Scale · San Francisco, CA (Onsite) · On-site

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About Evolutionary Scale

ESM3. Enabling scientists to understand, imagine, and create proteins. Backed by Lux.

About the role

Biohub is seeking a Scientist II to lead the scaling of our imaging and data-generation pipeline. This role will set throughput targets, find the bottlenecks that matter most, and work hands-on with the sample-prep, imaging, and computation teams to remove them — at the bench, at the microscope, and at the keyboard.

What they're looking for

  • Improve multi-specimen acquisition, instrument uptime, and cross-instrument reproducibility on the group's light-sheet microscopes, pushing sustained throughput toward the platform's practical limits
  • Establish reproducible SOPs, QC gates, and monitoring to ensure improvements persist as the team, instruments, and datasets scale — and to measure throughput, not assume it
  • Serve as the connective tissue between the group and Biohub's shared platforms, removing cross-team bottlenecks and helping the group hit its shared throughput milestones
  • Mentor and technically guide team members, translate scaling strategy into concrete engineering and experimental plans, and help recruit as the effort grows
  • Document architectures, protocols, release methods, code, and data for the community, in keeping with Biohub's open-science ethos
More about this role

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.

The Biohub is a group of nonprofit research institutes that bring together scientists, engineers, and physicians with the goal of pursuing grand scientific challenges on 10- to 15-year time horizons. The Biohub focuses on understanding underlying mechanisms of disease and developing new technologies that will lead to actionable diagnostics and effective therapies.

Our Vision

  • We pursue large scientific challenges that cannot be pursued in conventional environments
  • We enable individual investigators to pursue their riskiest and most innovative ideas
  • The technologies developed at the Biohub facilitate research by scientists and clinicians at our home institutions and beyond

Diversity of thought, ideas, and...

Read the full posting on Evolutionary Scale's site ↗

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