Startups · AI

Founding Scientist (Synthetic Genomics)

Exonic · San Francisco, CA, US · On-site

← All jobs
About Exonic

Exonic is an AI-native cell and gene therapeutics company. Backed by Y Combinator.

About the role

You would work directly with the founder as one of the first people in the company.

What they're looking for

  • Molecular biology, synthetic biology, regulatory genomics, or gene therapy
  • Mammalian cell culture and cell-based assays
  • Cloning, plasmid design, transfection, qPCR/ddPCR, sequencing, flow, luciferase, or related workflows
  • AAV biology/manufacturing experience is a major plus
More about this role

Exonic is building AI systems for programmable biology.

We train multimodal foundation models on large-scale biological datasets to design synthetic non-coding DNA. We experimentally validate our AI-designed systems in mammalian cells, with current applications in cell-type targeting and viral vector biomanufacturing.

Our core focus is synthetic regulatory DNA. We have already generated strong in vitro cell-type targeting results and are expanding our internal experimental platform in San Francisco.

We are looking for an ambitious experimental scientist to take ownership of Exonic’s wet-lab work and help push the platform into new directions.

You would work directly with the founder as one of the first people in the company.

  • Own and execute experimental validation of AI-designed regulatory DNA
  • Design and run cell-based assays for synthetic enhancer and expression systems
  • Help advance programs in cell-type targeting and AAV manufacturing
  • Help shape Exonic’s experimental roadmap as the company grows
  • Molecular biology, synthetic biology, regulatory genomics, or gene therapy
  • Mammalian cell culture and cell-based assays
  • Cloning, plasmid design, transfection, qPCR/ddPCR,...

Read the full posting on Exonic's site ↗

Science

Build your edge while you search

Free tools for founders and investors, plus VC Unfiltered, our take on startups, venture and the people who build them.