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Director, Pharmacology

Flagship Pioneering · Somerville, MA USA · On-site

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About Flagship Pioneering

Pioneering Partnerships Latest News.

About the role

What if you could join a rapidly growing company and play a critical role in bringing new medicines to patients through looking at and treating disease in a revolutionary way.

What they're looking for

  • PhD in biology, pharmacology, or a related scientific discipline, with 10-15+ years of relevant experience in biotech or pharmaceutical drug discovery and development
  • Strong foundation in preclinical pharmacology with demonstrated experience translating biology into in vivo efficacy and PK/PD insight
  • Experience connecting in vitro findings to in-vivo outcomes, including target engagement, exposure-response relationships, and translational biomarker strategy
  • Exposure to DMPK and ability to partner effectively with DMPK scientists on program interpretation and advancement
  • Proven track record of working across biology, chemistry, pharmacology, and external collaborators to influence drug discovery strategy
  • Experience managing and interpreting outsourced pharmacology studies through CROs
More about this role

What if you could join a rapidly growing company and play a critical role in bringing new medicines to patients through looking at and treating disease in a revolutionary way.

What if you could join a fast-moving research organization and help shape translational strategy across a growing preclinical pipeline? Cellarity is seeking a highly strategic Sr. Director, Pharmacology to connect biology, pharmacology, DMPK, and translational science across inflammation and hematology programs. Reporting to the Sr. Director of Lab Science, this role will partner closely with biology, chemistry, DMPK, toxicology, external CROs, and scientific leadership to drive programs from early discovery through candidate selection.

  • Lead preclinical pharmacology strategy across multiple discovery programs, with a focus on translating in vitro biology and functional assay data into meaningful in vivo outcomes.
  • Drive PK/PD interpretation, exposure-response assessment, target coverage analysis, and translational biomarker strategy to inform program decisions.
  • Integrate data across biology, pharmacology, medicinal chemistry, and DMPK to build clear scientific narratives and guide candidate...

Read the full posting on Flagship Pioneering's site ↗

Preclinical Development & Translational...

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