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Senior Director / Vice President, Machine Learning (Generative Chemistry)

Flagship Pioneering · Cambridge, MA USA · On-site

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About Flagship Pioneering

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About the role

FL117 , a venture-back stealth AI x bio startup, is seeking a highly skilled Sr. Director/VP ML, Generative Chemistry . Here you will lead AI/ML and cheminformatics projects building the next-gen multi-modal generative models for biomolecular design. You will define and deliver pragmatic AI strategies, oversee method and platform development (ex: systems design, drug design, molecular modeling, LLM/agentic workflows), and ensure rigor in model development, benchmarking, and scaling.

What they're looking for

  • MSc or PhD in Computer Science, AI/ML, Physics, Biophysics, or a related field
  • 7+ years of experience scientific/engineering/computational in Pharma or Biotech settings, industry AI/ML experience preferred
  • Experience driving results directly or indirectly through teams of engineers/scientists in dynamic, fast paced, entrepreneurial, and technical environments
  • Clear evidence of sustained independent thought and creativity driving high impact, across drug development and chemistry AI/ML projects
  • Successful track record of leadership and contribution to decision making on progression of AI/ML models within projects or programs
  • Depth across multiple core tools and concepts, including Python, modern ML frameworks (PyTorch or JAX/TensorFlow), version control, databases, deep learning architectures, and relevant informatics software
More about this role

FL117 , a venture-back stealth AI x bio startup, is seeking a highly skilled Sr. Director/VP ML, Generative Chemistry . Here you will lead AI/ML and cheminformatics projects building the next-gen multi-modal generative models for biomolecular design. You will define and deliver pragmatic AI strategies, oversee method and platform development (ex: systems design, drug design, molecular modeling, LLM/agentic workflows), and ensure rigor in model development, benchmarking, and scaling. You will manage the computational team split across AI/ML, molecular simulations, and cheminformatics, directly influencing company building decisions. We are looking for independent leaders, excited to work on ambitious projects in a fast-paced environment to push the frontier of AI-powered drug discovery.

  • Program Leadership : Lead development, implementation, control, and reporting of several AI/ML or computational projects within assigned ventures in line with broader strategic plans of PI and Flagship, budgets, and timelines.
  • Technical Ownership : Take a specialized technical role on project teams to oversee method development, pipeline development, and LLM based agent/workflow design; drive...

Read the full posting on Flagship Pioneering's site ↗

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