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Senior Research Associate / Associate Scientist, Nonclinical

Flagship Pioneering · Cambridge, MA USA · On-site

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About Flagship Pioneering

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About the role

Alltrna is looking for a hands-on scientist to join our Nonclinical team, where we test how well our engineered tRNAs work across a range of preclinical disease models. The ideal candidate is a strong cell and molecular biologist who is detail-oriented, intellectually curious, and energized by being part of a collaborative, fast-paced, small-company environment. Found on 1752vc Careers, the job board for startup and VC roles.

What they're looking for

  • BS or MS in biology, biochemistry, pharmacology, or a related field
  • Minimum BS with 4+ years or MS with 2+ years of hands-on laboratory experience in academia, biotechnology, or the pharmaceutical industry, more experience required at Associate scientist level
  • Strong experience in mammalian cell culture, including primary cells and cell lines, stem cell experience is a plus
  • Experience with cell line characterization and development, including growth curves, kill curves, clonal expansion, and mycoplasma testing
  • Hands-on experience with DNA/RNA delivery methods, such as transfection, lentiviral or AAV transduction, electroporation, or LNP-based delivery
More about this role

Alltrna is looking for a hands-on scientist to join our Nonclinical team, where we test how well our engineered tRNAs work across a range of preclinical disease models. The ideal candidate is a strong cell and molecular biologist who is detail-oriented, intellectually curious, and energized by being part of a collaborative, fast-paced, small-company environment.

Working closely with the Nonclinical team, this individual will select, develop, and optimize the assays we use to measure tRNA activity and efficacy. These include cell-based assays in primary cells and hepatocyte models to the RNA and protein readouts that support in vivo studies. The candidate will design, execute and analyze data that support platform expansion and drive early-stage programs into clinical development. This role will have opportunities to propose new ideas, collaborate with groups across the company and participate in broader data reviews and decision-making.

We are hiring at the Senior Research Associate or Associate Scientist level, depending on experience. We are looking for someone who takes ownership of their experiments, works carefully and efficiently, and can troubleshoot technical challenges...

Read the full posting on Flagship Pioneering's site ↗

Preclinical Development & Translational...

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