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Principal Statistical Methodology Data Scientist

Genentech · South San Francisco · On-site

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About Genentech

Genentech discovers, develops, manufactures and commercializes treatments for patients with serious and life-threatening medical conditions. Backed by North Carolina Biotechnology Center.

About the role

The Statistical Methodology Data Scientists play a strategic role in enabling the adoption of fit-for-purpose statistical methodologies to drive scientific rigor and decision-making excellence. This team serves as a center of excellence focused on consultation, education, and outreach to ensure that innovative and appropriate methods are applied across programs and portfolios. You serve as a methodological thought partner to study teams, providing expert guidance on complex design and analysis across programs

What they're looking for

  • You hold a PhD in Biostatistics, Statistics, Data Science, Computer Science, or a related quantitative discipline
  • You have 6+ years of experience designing and applying advanced analytics to complex biomedical data in clinical trial research
  • You bring deep expertise in statistical computing and advanced modeling, with a track record of developing novel or custom analytical solutions
  • You are recognized as a technical expert and thought partner within the organization or broader field
  • You have experience mentoring others and contributing to internal standards, strategy, or capability development
  • You show respect for cultural differences when interacting with colleagues in the global workplace
More about this role

The Position

The Statistical Methodology Data Scientists play a strategic role in enabling the adoption of fit-for-purpose statistical methodologies to drive scientific rigor and decision-making excellence. This team serves as a center of excellence focused on consultation, education, and outreach to ensure that innovative and appropriate methods are applied across programs and portfolios.

Statistical Methodology Data Scientists collaborate closely with project teams, biostatisticians, and cross-functional stakeholders to identify methodological needs, prototype solutions (e.g., estimand frameworks, trial simulations, covariate adjustment strategies), and support scalable adoption through training, templates, and open source software/tools. They engage in portfolio-level analyses, scenario modeling, and quantitative frameworks that inform go/no-go decisions and optimize clinical strategy.

The team also maintains key external relationships, representing the company in consortia, scientific working groups, and regulatory collaborations to stay at the forefront of methodological advances in the pharmaceutical industry.

You serve as a methodological thought partner to study teams,...

Read the full posting on Genentech's site ↗

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