Startups · AI

Senior Associate Scientist I/II, Purification Sciences

Iambic Therapeutics · San Diego HQ · On-site

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About Iambic Therapeutics

Iambic has created a cutting-edge AI-driven platform to tackle the most challenging design problems in drug discovery and address unmet patient need. Backed by Sequoia.

About the role

We are seeking a motivated and hands-on Senior Associate Scientist I/II, Purification Sciences to support small-molecule drug discovery. This individual will perform chromatography-based purification, with a focus on preparative LC and preparative SFC, supporting medicinal chemistry and high-throughput chemistry efforts.

More about this role

JOB SUMMARY

We are seeking a motivated and hands-on Senior Associate Scientist I/II, Purification Sciences to support small-molecule drug discovery. This individual will perform chromatography-based purification, with a focus on preparative LC and preparative SFC, supporting medicinal chemistry and high-throughput chemistry efforts.

The ideal candidate will have practical laboratory experience with chromatographic purification and a strong interest in developing expertise in separation science, instrumentation, and high-throughput purification workflows. Experience with instrument maintenance and troubleshooting is highly desirable. This position will be based in our San Diego Headquarters.

KEY RESPONSIBILITIES

Perform routine and moderately complex small-molecule purification using preparative LC and SFC, supporting medicinal chemistry and high-throughput chemistry workflows.

Develop and optimize purification methods, including column/mobile-phase selection, gradients, sample loading, and fraction collection.

Operate prep LC, prep SFC, analytical LC, and LC/MS systems and perform analytical QC of purified compounds.

Perform routine instrument maintenance and troubleshoot common...

Read the full posting on Iambic Therapeutics's site ↗

Science

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