At insitro, we are building a different kind of drug company to bring better drugs faster to the patients who can benefit most. Through the power of machine learning (ML) and data at scale, we decode the complexities of biology to unlock transformative new... Backed by SoftBank VF, a16z and GV.
About the role
insitro is a physical AI company dedicated to unlocking causal human biology and accelerating the delivery of better medicines to patients. Our unique Virtual Human™ platform identifies novel, high-impact genetic intervention points, which our TherML™ platform translates into therapeutics—whether small molecules, biologics, or oligos.
What they're looking for
- Qualifications and previous experience: A bachelor’s or master’s degree in biology, biochemistry, or related discipline with at least 2 years of relevant experience in the biotech/biopharma industry
- Cell culture and iPSC-CM Expertise: Deep hands-on experience in iPSC culture, cardiac directed differentiation and iPSC-CM model characterization in 2D (monolayer) format. Prior experience in 3D/engineered heart tissue platforms or organoids is a plus
- Genetic Disease Modeling: Previous experience developing genetic iPSC-CM disease models — patient-derived lines, CRISPR-edited isogenic pairs — to study cardiovascular mechanisms
- Cardiovascular Biology: Background in cardiomyocyte biology and/or cardiovascular disease is preferred
- Molecular Assays: Hands-on expertise in molecular assays, such as PCR, RT-qPCR, Western Blot and immunofluorescence
- Scientific Communication: Track record of executing rigorous experiments and communicating findings clearly in publications, presentations or internal reports
More about this role
insitro is a physical AI company dedicated to unlocking causal human biology and accelerating the delivery of better medicines to patients. Our unique Virtual Human™ platform identifies novel, high-impact genetic intervention points, which our TherML™ platform translates into therapeutics—whether small molecules, biologics, or oligos. With multiple programs in metabolic disease and neuroscience advancing toward the clinic, and our first IND submission slated for the second half of this year, we are at a pivotal inflection point.
We are seeking an Associate Scientist III to join our cardiac disease biology team. In this role, you will support the development and application of iPSC-derived cardiomyocyte (iPSC-CM) models to study the genetic and molecular underpinnings of cardiovascular disease — working at the intersection of human stem cell biology, cardiac physiology, and scalable experimental platforms to generate the datasets that fuel our ML-driven drug discovery efforts. You will design and execute experiments, optimize differentiation workflows, develop functional and scalable functional assays to connect cellular phenotypes to disease mechanisms and therapeutic...
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