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Director, Clinical Business Operations

Maze Therapeutics · South San Francisco, CA · On-site

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About Maze Therapeutics

Backed by a16z and GV.

About the role

At Maze Therapeutics, we believe precision medicine has the power to transform the lives of patients with both common and rare diseases. As Director, Clinical Business Operations, you will serve as a strategic business partner to the Head of Clinical Operations and the Clinical Development organization.

What they're looking for

  • Bachelor's degree in Business, Finance, Life Sciences, Healthcare Administration, or a related field
  • 10–12+ years of experience in Clinical Business Operations, Clinical Finance, Strategic Sourcing, Clinical Operations, or related business roles within biotechnology, pharmaceutical, or CRO organizations
  • Extensive experience developing and managing global clinical trial budgets across all phases of clinical development
  • Demonstrated success negotiating CRO, vendor, and investigator site budgets, including Master Service Agreements, work orders, study budgets, site budgets, and change orders
  • Strong understanding of clinical development, outsourcing models, fair market value methodologies, vendor contracting, and financial planning processes
  • Experience partnering closely with Finance on monthly accruals and forecasting, annual budgeting, long-range planning, and financial governance
More about this role

At Maze Therapeutics, we believe precision medicine has the power to transform the lives of patients with both common and rare diseases. As Director, Clinical Business Operations, you will serve as a strategic business partner to the Head of Clinical Operations and the Clinical Development organization. Working closely with Finance and cross-functional stakeholders, you will provide direction for the financial planning, budgeting, contracting, and operational business processes that support efficient and predictable clinical trial execution.

In partnership with the Head of Clinical Operations, Oversight Directors, Study Leads, and Clinical Development functional leaders, you will oversee study and program budgets, financial forecasting, vendor financial management, and clinical business operations across the development portfolio. You will help build scalable processes, establish budgeting standards, and provide the financial insights needed to support informed business decisions while maintaining sound fiscal stewardship.

This role requires a highly collaborative professional who enjoys solving complex operational challenges and working across Clinical Operations, Safety,...

Read the full posting on Maze Therapeutics's site ↗

Clinical Operations

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