Backed by a16z and GV.
About the role
At Maze Therapeutics, we believe precision medicine has the power to transform the lives of patients with both common and rare diseases. As an Oversight Director, Clinical Operations supporting an asset spanning our CKD and PKU portfolio, you will provide strategic and operational direction across the full development lifecycle.
What they're looking for
- Demonstrated success providing operational direction across multiple studies within a development program, driving strategy, execution, and delivery of key program milestones
- Proven experience guiding and developing high-performing Clinical Operations teams, including direct management, coaching, and mentoring of Study Leads and other Clinical Operations professionals
- Deep expertise in global clinical trial operations, including FDA, EMA, ICH-GCP, and other applicable regulatory requirements, with a strong track record of maintaining inspection readiness
- Extensive experience developing and overseeing CRO and vendor partnerships, including governance, performance management, contract negotiations, and budget accountability
- Strong financial acumen with experience managing large, complex clinical trial budgets, forecasting, and resource planning
- Demonstrated ability to identify operational risks, facilitate cross-functional problem-solving, and contribute to strategic planning in a fast-paced development environment
More about this role
At Maze Therapeutics, we believe precision medicine has the power to transform the lives of patients with both common and rare diseases. As an Oversight Director, Clinical Operations supporting an asset spanning our CKD and PKU portfolio, you will provide strategic and operational direction across the full development lifecycle. You will be responsible for the successful execution of multiple studies within your assigned program, ensuring high-quality clinical trials are delivered on time, within budget, and in accordance with quality and regulatory expectations.
Working closely with the Clinical Science Lead, you will partner in guiding the Clinical Development Sub-Team, providing strategic direction and operational oversight to advance the development program. You will support and develop Study Leads and Clinical Operations team members, establish and oversee CRO and vendor strategies, and maintain accountability for study execution, operational risk management, resource planning, financial oversight, and inspection readiness across your assigned asset.
In partnership with the Head of Clinical Operations, you will help shape the operational strategy for your development program,...
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