NewLimit is extending human healthspan by unlocking regenerative potential. Backed by Kleiner Perkins.
About the role
NewLimit is seeking a Scientist to join our Delivery Sciences team. In this role, you will development formulations, purification processes, and characterization methods for lipid nanoparticle (LNP) drug products. NewLimit’s reprogramming medicines rely upon these LNP chemistries to carry reprogramming payloads to target cells and tissues throughout the body.
What they're looking for
- Ph.D. in Biomedical Engineering, Chemical Biology, Pharmaceutical Sciences, or a related discipline or equivalent industry experience
- Experience formulating LNPs with diverse lipid components for nucleic acid delivery
- Experience with purification techniques, including dialysis, Tangential Flow Filtration (TFF), ultracentrifugation, and sterile filtration
- Proficiency in LNP analysis using dynamic or multi-angle light scatting, liquid chromatography, and standard molecular biology assays (ELISA, qPCR, spectroscopy)
More about this role
NewLimit is a biotechnology company working to radically extend human healthspan. We’re developing medicines to treat aging by reprogramming the epigenome, a new therapeutic mechanism to restore youthful function in aged cells. We’ve built the world’s leading experimental and artificial intelligence system to discover reprogramming medicines at massive scale. Our first products are focused on restoring youthful metabolic, endothelial, and immune function.
NewLimit is seeking a Scientist to join our Delivery Sciences team. In this role, you will development formulations, purification processes, and characterization methods for lipid nanoparticle (LNP) drug products. NewLimit’s reprogramming medicines rely upon these LNP chemistries to carry reprogramming payloads to target cells and tissues throughout the body.
The ideal candidate possesses a deep technical understanding of LNP assembly via various mixing methods, expertise in downstream purification, and hands-on experience with advanced analytical characterization techniques.
- Formulate, purify, and characterize LNPs for nucleic acid delivery
- Collaborate with the Epigenetic Editing and Product teams (Immunology, Metabolism,...
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