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Senior Scientist / Scientist, In Vivo Pharmacology

NewLimit · South San Francisco · On-site

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About NewLimit

NewLimit is extending human healthspan by unlocking regenerative potential. Backed by Kleiner Perkins.

About the role

NewLimit is seeking a talented Scientist / Senior Scientist of In Vivo Pharmacology to join our Translational Sciences team. This critical role designs and executes in vivo studies to evaluate pioneering epigenetic reprogramming therapeutics across our entire portfolio. As a subject matter expert in nonclinical and PK/PD study design, you will lead in vivo pharmacology strategies, collaborate cross-functionally with therapeutic area teams, and directly drive therapeutic candidate selection.

What they're looking for

  • Ph.D. in pharmacology, physiology, biology or a related field or equivalent industry experience (5+ years for Scientist, 8+ years for Senior Scientist)
  • Demonstrated experience designing and executing in vivo pharmacology studies (PK, PD, efficacy, dose-range finding) in rodent models
  • Experience with study design, dosing regimens, and route-of-administration selection
  • Experience analyzing and interpreting in vivo pharmacology data to inform program decisions
  • Experience leading project workflows and providing technical mentorship to junior laboratory staff
  • History of contributing to a drug development program at the pre-clinical or clinical development stage
More about this role

NewLimit is a biotechnology company working to radically extend human healthspan. We’re developing medicines to treat age-related diseases by reprogramming the epigenome, a new therapeutic mechanism to restore regenerative potential in aged and diseased cells. We leverage functional genomics, pooled perturbation screening, and machine learning models to unravel the biology of epigenetic aging and disease using experiments of unprecedented scale.

NewLimit is seeking a talented Scientist / Senior Scientist of In Vivo Pharmacology to join our Translational Sciences team. This critical role designs and executes in vivo studies to evaluate pioneering epigenetic reprogramming therapeutics across our entire portfolio. As a subject matter expert in nonclinical and PK/PD study design, you will lead in vivo pharmacology strategies, collaborate cross-functionally with therapeutic area teams, and directly drive therapeutic candidate selection.

  • Design, execute, and interpret in vivo pharmacology studies (PK/PD, efficacy, dose-response) across multiple disease models and therapeutic programs
  • Collaborate with Epigenetic Editing, Predictive Modeling, and other therapeutic area teams to...

Read the full posting on NewLimit's site ↗

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