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Sr. Scientist, Spatial Biology

NOETIK · South San Francisco · On-site

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About NOETIK

Noetik is an AI-native biotechnology company that applies self-supervised machine learning to large-scale human multimodal spatial omics datasets with the aim of developing precision cancer therapies. Backed by DCVC (Data Collective).

About the role

In this role, we are seeking a highly motivated and detail-oriented Senior Scientist to join our team at the frontier of spatial biology and AI, driving hands on execution, protocol development, and quality standards for spatial biology experiments on human tissue samples in a lab built to fuel next-generation AI models.

What they're looking for

  • PhD in molecular biology, genomics, cell biology, biomedical engineering, or a related field
  • 2-5+ years of industry hands-on experience with spatial transcriptomics (CosMx, Xenium, MERFISH…), direct CosMx experience strongly preferred
  • Experience with spatial proteomics platforms (e.g., CosMx Protein, Akoya PhenoCycler, Lunaphore..) and immunofluorescence panel design are highly desirable
  • Proven ability to independently troubleshoot wet-lab and imaging-based assay failures, tracing issues back to root cause
  • Solid knowledge of spatial transcriptomics data QC metrics: transcript count distributions, segmentation quality, dropout/housekeeping-gene diagnostics, batch effects, and spatial artifacts
  • Comfortable enforcing standards across a team that includes both junior and more senior colleagues — this role requires leadership as well as technical skill
More about this role

NOETIK is a frontier therapeutics company harnessing AI to deeply understand human biology and redefine clinical outcomes in oncology. Leveraging the largest proprietary multimodal oncology dataset of its kind, uniquely integrating deep spatial profiling with routine clinical assays, NOETIK’s foundation AI models precisely match therapeutic targets to patient subpopulations and accurately predict clinical efficacy. This AI-first approach elevates therapeutic development from probabilistic guesswork to precision science.

In this role, we are seeking a highly motivated and detail-oriented Senior Scientist to join our team at the frontier of spatial biology and AI, driving hands on execution, protocol development, and quality standards for spatial biology experiments on human tissue samples in a lab built to fuel next-generation AI models. The ideal candidate will have deep hands-on experience with in situ hybridization & proteomics techniques, spatial data analysis and demonstrate strong troubleshooting, mentorship, and organizational skills. This is an exciting opportunity to contribute to a multidisciplinary laboratory environment at the interface between Spatial Biology and AI...

Read the full posting on NOETIK's site ↗

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