Pivotal Life Sciences specializes in providing capital to innovative companies developing therapeutic products to address major unmet medical needs.
About the role
Interested candidates will click Apply to proceed to our application portal and will need to submit a resume and cover letter detailing relevant experience. To be considered for the role, applicants must be:
What they're looking for
- Support the design, planning, and execution of in vivo rodent studies evaluating delivery, biodistribution, editing efficiency, pharmacodynamic activity, tolerability, and related preclinical endpoints
- Perform hands-on in vivo study activities under approved protocols, which may include animal handling, dosing support, clinical observations, body weight tracking, sample collection, necropsy support, and tissue harvest
- Prepare study materials, dosing solutions, collection supplies, labels, chain-of-custody documentation, and sample inventories to ensure studies run smoothly and reproducibly
- Process blood, plasma, serum, bone marrow, spleen, liver, and other tissues for downstream molecular, cellular, and protein-based analyses, including nucleic acid and protein extraction workflows
- Coordinate with internal scientists and external partners or CROs to align study timelines, protocols, sample logistics, data transfers, and documentation requirements
- Maintain accurate electronic and paper study records, including protocols, worksheets, sample maps, deviations, reagent logs, and raw data consistent with data integrity and reproducibility expectations
More about this role
Senior / Principal Research Associate, In Vivo Studies
Job Type: Full time, Onsite
About Us
We are an innovative, stealth-mode biotech focused on developing best-in-class delivery for in vivo gene editing.
Job Summary
The In Vivo Studies team is hiring a Senior / Principal Research Associate to support the planning, execution, and analysis of in vivo pharmacology and biodistribution studies that advance our preclinical programs. This is a hands-on role for a scientifically rigorous, highly organized researcher who can execute rodent studies, collect high-quality samples, maintain strong study records, and partner closely with Translational Research, Delivery, Editing, and Program teams. The location for this position is expected to be onsite in our Boston lab.
Responsibilities
- Support the design, planning, and execution of in vivo rodent studies evaluating delivery, biodistribution, editing efficiency, pharmacodynamic activity, tolerability, and related preclinical endpoints.
- Perform hands-on in vivo study activities under approved protocols, which may include animal handling, dosing support, clinical observations, body weight tracking, sample collection, necropsy support, and...
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