The next frontier is authoring new biology, and with AI, we have the power to write the future—creating solutions that transform medicine, agriculture, and beyond. Backed by Insight and Air Street.
About the role
Profluent is seeking a Controller to serve as the company's senior accounting leader and architect of its finance infrastructure at a pivotal stage of growth. This is a true builder role: you will own the full accounting function, from close and financial reporting to technical accounting, equity, treasury, and compliance. You’ll also be designing the systems, controls, and processes required for a future public-company operating environment.
What they're looking for
- Bachelor's degree in Accounting or Finance, active CPA license
- 10+ years of progressive accounting experience, with at least 3 years in a Controller or senior accounting leadership role, preferably within a Big 4 or similar environment
- Prior experience in a pre-IPO or high-growth venture-backed company environment required (e.g., biotech, tech)
- Demonstrated experience with NetSuite, including implementation, migration, or optimization (experience migrating from QuickBooks or similar legacy system strongly preferred)
- Hands-on experience designing and maintaining internal control frameworks
- Strong command of U.S. GAAP, ability to independently research and document technical accounting positions
More about this role
Profluent is the frontier AI lab for biology. Profluent builds powerful foundation models for all of life's molecules, unlocking solutions that transform medicine, agriculture, and beyond. Founded in 2022 and headquartered in Emeryville, CA, Profluent is backed by leading investors including Altimeter Capital, Bezos Expeditions, Spark Capital, Insight Partners, Air Street Capital, AIX Ventures, and Convergent Ventures and has raised over $150M to date.
Profluent is seeking a Controller to serve as the company's senior accounting leader and architect of its finance infrastructure at a pivotal stage of growth. This is a true builder role: you will own the full accounting function, from close and financial reporting to technical accounting, equity, treasury, and compliance. You’ll also be designing the systems, controls, and processes required for a future public-company operating environment.
The right candidate brings accounting experience from a high-growth company (with exposure to CRO accruals, R&D program cost tracking, and ASC 718), hands-on NetSuite (or similar) implementation or migration experience, and the technical rigor to independently research and document complex GAAP...
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