Tessera Therapeutics is an early-stage life sciences company pioneering Gene Writing™, a new biotechnology designed to offer scientists and doctors the…. Backed by SoftBank VF.
About the role
You are a skilled and self-motivated individual who can optimize and implement processes for synthesizing and purifying complex oligonucleotides. You can operate in a fast-paced environment, troubleshoot instruments, and document operations independently and as part of a team. You will have the opportunity to organize and present results within the group and interface with other teams, so strong communication skills are critical. You enjoy overcoming challenges in collaboration with colleagues.
What they're looking for
- BS/MS in Chemistry, Biochemistry, Chemical Engineering, or related field with 5+ years (BS) or 3+ years (MS) of relevant industry experience
- Experience with upstream and downstream processing of oligonucleotides
- Must have experience with Mermade192 and Mermade12 synthesizers
- Experience with Äkta100 oligonucleotide synthesizer is a plus
- Experience with HPLC purification and analytics of guide RNA preferred
- Experience with enzymatic ligation techniques is a plus
More about this role
- BS/MS in Chemistry, Biochemistry, Chemical Engineering, or related field with 5+ years (BS) or 3+ years (MS) of relevant industry experience
- Experience with upstream and downstream processing of oligonucleotides
- Must have experience with Mermade192 and Mermade12 synthesizers
- Experience with Äkta100 oligonucleotide synthesizer is a plus
- Experience with HPLC purification and analytics of guide RNA preferred
- Experience with enzymatic ligation techniques is a plus
- Experience using ELNs to document experimental results is a plus
- Performing small scale, high throughput internal production of guide RNA to support platform research and pre-clinical activities
- Optimizing synthetic reactions and purification methods of drug candidates to ensure scalable and cost-effective processes for oligonucleotide manufacturing
- Working in collaboration with the Internal Manufacturing team during process transfer
- Participating in cross-functional teams and training to gain familiarity in all stages of oligonucleotide research and manufacturing
You are a skilled and self-motivated individual who can optimize and implement processes for synthesizing and purifying complex...
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