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Principal Scientist, Biology

Xaira · South San Francisco, California, United States · On-site

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About Xaira

We’re pioneering the discovery and development of life-changing medicines through the transformative power of artificial intelligence. Backed by Lightspeed, NEA and Sequoia.

About the role

Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification.

What they're looking for

  • PhD in Immunology or a related field with 6+ years of relevant experience
  • Track record of impact through first-author publications, posters, and presentations at meetings
  • Demonstrated ability to independently define research strategy, plan and oversee complex experiments, and interpret data to guide program direction
  • Experience generating and advancing novel target hypotheses, with the scientific judgment to prioritize among competing ideas
  • Strong expertise in in vitro and ex vivo immunology, including primary immune assays, co-culture systems, target cell depletion assays, and high-parameter flow cytometry
  • Single-cell RNA sequencing (scRNAseq), CRISPR/Cas9, and omics data analysis experience is a plus
More about this role

Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London.

About the Role

Xaira Therapeutics is seeking a lab-based Principal Scientist in Inflammation and Immunology to join our Biology & Pharmacology department. This role is ideal for someone who combines hands-on research expertise with strategic program leadership, has experience working with primary human and mouse immune cells, including ex vivo tissue systems, and is excited to shape and drive therapeutic program strategy.

In this role, you will set the scientific direction for one or more therapeutic programs, generate and advance new biology...

Read the full posting on Xaira's site ↗

Biology & Pharmacology

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