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Senior Software Engineer, X-Scientist

Xaira · South San Francisco, California, United States · On-site

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About Xaira

We’re pioneering the discovery and development of life-changing medicines through the transformative power of artificial intelligence. Backed by Lightspeed, NEA and Sequoia.

About the role

Xaira is pioneering an AI-native approach to discovering and developing the next generation of life-changing medicines. We are building predictive and agentic AI systems across drug discovery, and the X-Scientist team accelerates this mission by making AI-assisted science reliable, usable, and scalable across drug discovery workflows.

What they're looking for

  • Strong Python engineering fundamentals, with clean, typed, tested, maintainable code
  • Experience building at least one of the following: a production library, CLI, API, SDK, backend service, workflow system, or developer platform
  • Familiarity with LLM application development, agent frameworks, tool calling, MCP-style interfaces, or orchestration systems
  • Comfort working with complex systems that combine multiple components, external calls, domain-specific logic, and evolving user needs
  • Good instincts for abstraction, error handling, reliability, and designing software that can grow across use cases
  • Strong communication skills and ability to work in a collaborative, multidisciplinary environment
More about this role

Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London.

Xaira is pioneering an AI-native approach to discovering and developing the next generation of life-changing medicines. We are building predictive and agentic AI systems across drug discovery, and the X-Scientist team accelerates this mission by making AI-assisted science reliable, usable, and scalable across drug discovery workflows.

On the X-Scientist team, you will work at the intersection of AI, software engineering, and therapeutic discovery. You will collaborate closely with AI scientists, engineers, platform teams, and drug discovery...

Read the full posting on Xaira's site ↗

Computational Protein Design

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