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Scientific Operations Manager Associate Scientist Oligonucleotide Synthesis Analytical Sciences

Alloy Therapeutics · Remote (US) · Remote

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About Alloy Therapeutics

Alloy Therapeutics democratizes access to antibody discovery and biologics discovery technology to enable and advance drug discovery in antibodies and TCRs.

About the role

We are Alloy Therapeutics — a biotechnology ecosystem and Product Development Organization (PDO) empowering the global scientific community to make better medicines together. Through a community of partners, we democratize access to pre-competitive tools, technologies, services, and company creation capabilities that are foundational for discovering and developing therapeutic biologics.

What they're looking for

  • Set and defend turnaround time commitments by sequence class, modified sequences, difficult couplings, high-GC or structured regions, scarce amidites at intake rather than after a failed synthesis
  • Inventory Management Manage reagent, raw material, and consumable inventory against the production schedule, coordinating procurement and lot-level traceability as appropriate for research-grade work
  • Deviations, Root Cause Analysis & CAPA Lead structured root cause investigations of synthesis and QC deviations, author and track CAPAs to closure, and report deviation trends to leadership
  • Perform solid-phase oligonucleotide synthesis on automated synthesizers, including preparation of reagents, programming of sequences, and troubleshooting instrument issues
  • Conduct downstream processing steps such as cleavage, deprotection, purification (e.g., HPLC, SPE), and formulation
  • Execute analytical QC testing (e.g., HPLC, LC-MS, UV quantitation, capillary electrophoresis) and interpret results against acceptance criteria
More about this role

Role Location: Waltham, MA

The Company

We are Alloy Therapeutics — a biotechnology ecosystem and Product Development Organization (PDO) empowering the global scientific community to make better medicines together. Through a community of partners, we democratize access to pre-competitive tools, technologies, services, and company creation capabilities that are foundational for discovering and developing therapeutic biologics. The company facilitates affordable, non-exclusive access to the entire drug discovery community from academic scientists, small and medium biotech, to the largest biopharma. At Alloy, we believe our industry should compete on getting the best drugs to patients as quickly as possible, not exclusive access to the best platforms. As a reflection of our relentless commitment to the scientific community, we reinvest 100% of our revenue in innovation and access to innovation. May the Best Drug Win.

Alloy has evolved from a startup into a global product development organization operating 11 divisions across 5 research sites in 4 countries on 3 continents. Our model - Integrated Independence - combines centralized capabilities with entrepreneurial operating divisions....

Read the full posting on Alloy Therapeutics's site ↗

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