Backed by Atlas Venture.
About the role
Antares Therapeutics is seeking an accomplished, technically driven Sr. Scientist II/ Principal Scientist to join our Chemical Biology team. This is a senior individual-contributor role for a proteomics and mass spectrometry expert who can independently drive chemoproteomic target discovery and validation efforts, as well as hit identification and characterization, in support of our small molecule discovery portfolio. Found on 1752vc Careers, the job board for startup and VC roles.
What they're looking for
- PhD. in Analytical Chemistry, Biochemistry, Proteomics, Chemical Biology, or a related discipline with at a minimum 8+ years of relevant industry and/or postdoctoral experience
- Deep experience in operating and maintaining mass spectrometry and liquid chromatography instrumentation is required
- Expertise in MS-based proteomic methods to study protein/peptide modification, protein interactions, protein turnover, and/or targets using enrichment methods is required
- Experience in MS-based sample preparation and target enrichment approaches is required
- Experience in small molecule drug mechanisms of action (e.g., covalent ligands, molecular glues, PROTACs, etc.) is desirable
- Knowledge/experience with activity-based protein profiling (ABPP) is desirable
More about this role
Antares Therapeutics is seeking an accomplished, technically driven Sr. Scientist II/ Principal Scientist to join our Chemical Biology team. This is a senior individual-contributor role for a proteomics and mass spectrometry expert who can independently drive chemoproteomic target discovery and validation efforts, as well as hit identification and characterization, in support of our small molecule discovery portfolio. As a member of the team, you will develop and deploy novel mass spectrometry-based proteomic approaches for target identification, methods to elucidate mechanisms of action, and validate engagement through cycles of hit identification and SAR advancement. Achieving these objectives will involve the application of innovative chemoproteomic methodologies and the utilization of advanced HPLC and mass spectroscopy (MS) instrumentation, as well as participating in project teams. This position offers a unique opportunity to work in a collaborative, fast-paced environment at the intersection of chemistry and biology.
- Serve as the chemical biology functional lead on programs, reporting and presenting discovery evidence for multiple small-molecule programs
- Propose and...
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