Who we are. Arbor Biotechnologies, a clinical stage, next-generation gene editing company based in Cambridge, MA, is advancing a portfolio of first-in-class genomic medicines addressing serious diseases for which there are no existing functional cures, with a... Backed by Accel.
About the role
The Senior Clinical Trial Manager will lead day-to-day clinical trial operations for assigned early-phase studies of our gene-editing therapeutics in rare genetic diseases. Reporting to the Senior Director of Clinical Operations, this role will be responsible for study execution from start-up through close-out, including site oversight, CRO and vendor management, trial documentation, timelines, budgets, and operational issue resolution. Found on 1752vc Careers, the job board for startup and VC roles.
What they're looking for
- Lead day-to-day clinical trial operations across assigned studies, sites, CROs, laboratories, and vendors
- Manage study start-up, site activation, monitoring oversight, and close-out activities
- Own and manage study timelines, budgets, invoices, vendor deliverables, and key milestones
- Oversee study documentation and trial master file quality to support inspection readiness
- Review and provide operational leadership on clinical documents, including protocols, ICFs, CRFs, SAPs, CSRs, study plans, and related materials
- Partner with cross-functional study teams to drive study execution, resolve operational issues, and support achievement of study milestones
More about this role
Why this role matters.
The Senior Clinical Trial Manager will lead day-to-day clinical trial operations for assigned early-phase studies of our gene-editing therapeutics in rare genetic diseases. Reporting to the Senior Director of Clinical Operations, this role will be responsible for study execution from start-up through close-out, including site oversight, CRO and vendor management, trial documentation, timelines, budgets, and operational issue resolution.
In our lean biotech environment, this role requires a hands-on clinical operations leader who can manage multiple aspects of trial execution while partnering closely with internal teams, investigative sites, CROs, laboratories, and external vendors.
This role can be remote.
What you'll own.
- Lead day-to-day clinical trial operations across assigned studies, sites, CROs, laboratories, and vendors.
- Manage study start-up, site activation, monitoring oversight, and close-out activities.
- Own and manage study timelines, budgets, invoices, vendor deliverables, and key milestones.
- Oversee study documentation and trial master file quality to support inspection readiness.
- Review and provide operational leadership on clinical...
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