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Scientist, In Vitro Pharmacology

Arda Therapeutics · San Carlos, CA · On-site

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About Arda Therapeutics

Backed by Purple Arch Ventures.

About the role

Arda is seeking an experienced, self-driven scientist to lead in vitro pharmacology projects focused on developing the next-generation of immune-targeting therapies. This individual will play a pivotal role in developing and executing in vitro / ex vivo immunological assays to assess the efficacy of our therapeutic assets, with a particular emphasis on multispecific immune cell engagers. Found on 1752vc Careers, the job board for startup and VC roles.

What they're looking for

  • Either a PhD in Pharmacology, Immunology, or a related biological science, with a minimum of 2 years of industry, or a master’s degree and 6+ years of relevant industry experience
  • Demonstrated expertise in immunology and inflammatory disease space with a focus on developing medium to high throughout in vitro /ex vivo model systems
  • Strong background in immunology and/or inflammation research with experience in primary immune cell isolation, characterization, culture and differentiation
  • Proven track record of contributing to multiple projects and documenting work using electronic notebooks (benchling)
  • Excellent communication and collaboration skills, with the ability to work effectively in cross-functional teams
  • Hands-on approach with a desire to independently drive experimental design and execution
More about this role

Traditional pharmaceuticals modulate individual proteins and signaling pathways, aiming to nudge tissues and organs back toward health. But cells - not proteins - are the functional units of diseased tissue, and their behavior is governed by redundant networks that single-target drugs struggle to change. Arda Therapeutics offers a groundbreaking alternative: we target cells, not pathways. By depleting specific pathogenic cells that drive chronic diseases such as fibrosis and inflammation, we shut down the entire network of dysfunction at once, rather than blocking one of many redundant nodes.

What makes this possible is an explosion of single-cell data. Arda's discovery engine integrates multi-modal single-cell, spatial, and genetic data to pinpoint pathogenic cell states and the surface markers that distinguish them from healthy cells with unprecedented precision. We engineer targeted biologics that eliminate only the harmful cells, sparing healthy tissue and opening the door to greater efficacy and episodic treatment. Backed by leading life-science and technology investors - and built by a team that blends computational biology, drug development, and cell-depletion expertise -...

Read the full posting on Arda Therapeutics's site ↗

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