Startups

Software Engineer, Platform Infrastructure

Axiom Bio · South San Francisco · On-site

← All jobs
About Axiom Bio

Axiom provides frontier intelligence for human drug toxicity, helping scientists reduce unexpected toxicity earlier and develop safer medicines with less animal testing. Backed by Amplify Partners.

About the role

Build and operate the shared infrastructure behind Axiom’s scientific data pipelines, AI agents, research workflows, and Translate product. Own cloud infrastructure, compute, storage, databases, and networking, making systems reliable, secure, scalable, and cost-efficient. Found on 1752vc Careers, the job board for startup and VC roles.

What they're looking for

  • Python, SQL, asynchronous programming, APIs, and production backend systems
  • AWS, Modal, Docker, Terraform, cloud networking, and infrastructure as code
  • DuckDB/MotherDuck, Postgres, S3, Parquet, database migrations, backups, and recovery
  • Workflow orchestration, dependency management, distributed execution, checkpointing, retries, and durable state
  • Data versioning, lineage, reproducible pipelines, and automated consistency checks
  • IAM, SSO, OAuth/OIDC, workload identity, secrets management, and customer isolation
More about this role

Build the secure, reliable platform that powers Axiom’s scientific AI agents, experimental data pipelines, and products used by the largest pharmaceutical companies and AI labs in the world.

Axiom’s mission is to eliminate unexpected drug toxicity and unlock an abundance of ultra safe medicines. We are starting with the liver, where toxicity remains a leading cause of drug failure. Our high-throughput human liver safety platform combines advanced human cell systems with imaging, transcriptomics, mass spectrometry, and drug metabolism measurements. Our AI agents integrate these data with chemical structure, human exposure, and thousands of clinical reference compounds to predict whether a drug will be toxic in humans, why, and how to make it safer.

We work with seven of the world’s top twenty pharmaceutical companies to design safety into molecules from the earliest stages. This applied work feeds directly into our partnerships with leading frontier AI labs, turning real discovery challenges and experimental feedback loops into scientific skill trees and reinforcement learning environments that train increasingly superhuman scientists. We then deploy these frontier models to make...

Read the full posting on Axiom Bio's site ↗

Build your edge while you search

Free tools for founders and investors, plus VC Unfiltered, our take on startups, venture and the people who build them.