Patient-Centric Mission. Asset-Centric Approach. We’re pursuing our Orexin Receptor 2 Agonist Program to bring potentially transformative treatment options to patients with sleep-wake, neurological, neurodegenerative and neuropsychiatric disorders.... Backed by Foresite Capital.
About the role
Centessa Pharmaceuticals, a wholly owned subsidiary of Eli Lilly and Company, is a clinical-stage company developing orexin receptor 2 (OX2R) agonists as a new class of medicines for the treatment of narcolepsy and potentially other sleep-wake disorders. Centessa’s lead investigational candidate – cleminorexton (formerly ORX750) – is being developed for narcolepsy type 1, narcolepsy type 2, and idiopathic hypersomnia. Found on 1752vc Careers, the job board for startup and VC roles.
What they're looking for
- Education: B.S. or M.S. degree in Toxicology, Pharmacology, Cellular/Molecular Biology, Bioinformatics, or a related life sciences discipline
- With an M.S. degree: 6–8+ years of highly relevant biotechnology, pharmaceutical, or tier-one CRO industry experience
- With a B.S. degree: 8–10+ years of extensive industrial drug-development, data management, and toxicology operations experience
- Expert-level understanding of preclinical toxicology datasets , histopathology reporting structures, and study designs
More about this role
Centessa Pharmaceuticals, a wholly owned subsidiary of Eli Lilly and Company, is a clinical-stage company developing orexin receptor 2 (OX2R) agonists as a new class of medicines for the treatment of narcolepsy and potentially other sleep-wake disorders. Centessa’s lead investigational candidate – cleminorexton (formerly ORX750) – is being developed for narcolepsy type 1, narcolepsy type 2, and idiopathic hypersomnia. Centessa's OX2R agonist portfolio includes additional clinical and preclinical-stage assets with potential utility across a broader range of neurological, neurodegenerative, and neuropsychiatric conditions.
Headquartered in Boston, Massachusetts, Centessa was recognized as a Great Place to Work ® in 2026.
We are seeking an analytically elite, strategically minded Senior Scientist to join our Safety Assessment team. This is a 100% non-laboratory position designed for a seasoned bioscientist or toxicology operations expert who thrives at the intersection of dataset auditing, mechanistic evaluation, and cross-functional project leadership.
As a Senior Scientist, you will serve as a vital scientific and strategic hub connecting Centessa’s internal toxicology leaders with...
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