Denali Therapeutics brings the power of biotherapeutics to the whole body, including the brain. We discover, develop and deliver medicines for people living with serious diseases. Backed by GV.
About the role
We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients. Found on 1752vc Careers, the job board for startup and VC roles.
What they're looking for
- Lead complex, cross-functional, and external biomarker research programs within Translational Medicine
- Lead cross-functional teams that deliver therapeutic project team objectives
- Define biomarker strategies that generate clinical evidence of target engagement, pathway engagement, and disease-biomarker modulation, including surrogate or intermediate endpoints that support accelerated approval
- Direct the design, qualification, and implementation of biomarker assays in clinically relevant biosamples
- Author biomarker strategy and data packages for BLAs and other regulatory submissions, including briefing documents and health authority responses
- Interpret complex data sets and communicate results to scientific, clinical, and leadership audiences
More about this role
Denali Therapeutics Inc. is a biotechnology company pioneering a new class of biotherapeutics designed to cross the blood-brain barrier (BBB) using its proprietary TransportVehicle™ platform. With the first FDA-approved biologic specifically designed to cross the BBB, a clinically validated delivery platform and a growing portfolio of therapeutic candidates across all stages of development, we are advancing toward our goal of delivering effective medicines to transform the lives of people living with neurodegenerative diseases, lysosomal storage disorders and other serious diseases.
We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.
Partners with leaders across Discovery and Development to set biomarker strategy for large-molecule programs in rare, genetically defined, and neurodegenerative diseases. Shapes biomarker-driven clinical development plans that support dose selection, proof-of-concept, and deep patient phenotyping. Applies expert knowledge of drug development and regulatory science to move therapeutics through the clinic toward approval. Influences program direction and strengthens the...
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