ESM3. Enabling scientists to understand, imagine, and create proteins. Backed by Lux.
About the role
The Advanced Single Cell Technologies group provides critical single cell profiling and perturbation assays, technology, and expertise to the Biohub NY community. The goal of the platform is to develop cutting-edge single-cell technologies in collaborations related to studying human disease and the interaction of immune cells with human organs. More information can be found on the lab website ( https://biohub.org/single-cell-technology-platform/) . Found on 1752vc Careers, the job board for startup and VC roles.
What they're looking for
- Design, build and test prototypes for point-of-care sample processing, iterating based on performance data and optimizing for reproducibility
- Design mechanisms for controlled timing and sequencing of biochemical processes within a device (e.g., controlled reagent release, passive valving, or equivalent)
- Perform hands-on preparation and handling of biological specimens, and conduct assay validation experiments (e.g., timing precision, reagent activity, sample/cell quality at endpoint)
- Apply domain knowledge across device engineering, cell biology, and materials science to guide hardware design decisions
- Establish test protocols and acceptance criteria to ensure reproducible performance across prototype iterations and production lots
- Participate in discussions with project collaborators
More about this role
Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.
Our immune cell reprogramming team integrates foundational research on immunology and disease biology with AI-modeling to develop engineered cells that harness our own immune system to detect and treat early signs of age-related diseases, like cancer, Alzheimer’s, and Parkinson’s. These technologies will enable precise, context-dependent therapeutic responses only when and where it is needed. You can learn more about our work here .
Our work brings together three powerhouse universities - Columbia University, The Rockefeller University, and Yale University - into a single collaborative technology and discovery engine.
- Pursue large scientific challenges that cannot be pursued in conventional environments
- Enable...
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