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Principal Business Manager, Early Clinical Development (ECD)

Genentech · South San Francisco · On-site

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About Genentech

Genentech discovers, develops, manufactures and commercializes treatments for patients with serious and life-threatening medical conditions. Backed by North Carolina Biotechnology Center.

About the role

The Early Clinical Development (ECD) Business Manager acts as a key strategic advisor to the assigned Leadership Team and Senior Leaders within gRED ECD. Reporting directly to the ECD Chief of Staff, this role leads short- and long-term business planning, strategy formulation, resource allocation, budget oversight, and execution across the department. This position requires SSF on-campus presence between 3 to 4 times a week based on business demands. Found on 1752vc Careers, the job board for startup and VC roles.

What they're looking for

  • Education & Certifications: Bachelor’s degree required, project management or process improvement certifications (PMP, Six Sigma, Agile, Change Management) preferred
  • Experience: 5–10 years in business management, cross-functional initiatives, or operations programs (clinical development experience preferred)
  • Core Competencies: Expertise in strategic planning, project management, business process improvement, and team facilitation
  • Problem Solving & Innovation: Proactive problem solver skilled at challenging standard processes, proposing creative solutions, and adapting to fast-changing demands
  • Communication & Relationships: Strong written, oral, and presentation skills with a proven ability to build transparent, productive cross-functional relationships
  • Change Leadership: Demonstrated ability to develop and execute change management and communication strategies across the enterprise
More about this role

We advance science so that we all have more time with the people we love.

The Early Clinical Development (ECD) Business Manager acts as a key strategic advisor to the assigned Leadership Team and Senior Leaders within gRED ECD. Reporting directly to the ECD Chief of Staff, this role leads short- and long-term business planning, strategy formulation, resource allocation, budget oversight, and execution across the department. This position requires SSF on-campus presence between 3 to 4 times a week based on business demands.

  • Cross-Functional Collaboration: Fosters team alignment and builds networks across functions, enterprise teams, and external partners to achieve key milestones.
  • Talent & Team Engagement: Drives talent development, engagement programs, departmental workshops, and recognition initiatives to foster professional growth.
  • Strategic Leadership Partnership: Serves as a thought partner to executive leadership, advising on priorities, providing constructive challenge, and driving short- and long-term enterprise strategy.
  • Meeting Facilitation & Action Tracking: Structures leadership meetings with clear agendas, concise documentation, and rigorous follow-up on action...

Read the full posting on Genentech's site ↗

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