Genentech discovers, develops, manufactures and commercializes treatments for patients with serious and life-threatening medical conditions. Backed by North Carolina Biotechnology Center.
About the role
In this lab-based role, you will provide scientific and technical expertise in stem cell culture, induced pluripotent stem cell (iPSC)-derived systems, 3D cell and tissue models, and complex in vitro platforms. Responsibilities include culturing and characterizing advanced cellular models, designing and executing model development and qualification studies, establishing functional and phenotypic assays, analyzing and interpreting complex datasets, and maintaining rigorous, high-quality documentation. Found on 1752vc Careers, the job board for startup and VC roles.
What they're looking for
- Maintain and expand human stem cell and iPSC cultures, including differentiation, maturation, cryopreservation, quality control, and phenotypic characterization
- Design and execute experiments to establish the reproducibility, robustness, and biological relevance of complex in vitro models
- Develop and apply functional and phenotypic assays using approaches such as cytotoxicity and viability assays, immunofluorescence, confocal and high-content imaging, molecular profiling, and functional readouts
- Support the development and application of ocular complex in vitro models, including retinal, RPE, vascular, organoid, and co-culture systems, to address drug discovery and translational questions
- Apply rigorous experimental design, troubleshooting, and protocol optimization to establish reproducible and scalable workflows
- Analyze and interpret multidimensional datasets and clearly communicate findings, limitations, and recommendations to collaborators and stakeholders
More about this role
We advance science so that we all have more time with the people we love.
The Position
The Complex in Vitro Systems (CiS) Lab within the Department of Translational Safety is seeking a highly motivated Scientist 3/4 to develop, characterize, and qualify advanced human-relevant in vitro models to support Genentech’s mission of delivering safe and efficacious medicines. The CiS group partners closely with colleagues across Development Sciences, Translational Medicine, and Research to establish and implement innovative platforms that enable target assessment, drug discovery, and safety evaluation across a dynamic portfolio, novel modalities, and emerging therapeutic areas.
In this lab-based role, you will provide scientific and technical expertise in stem cell culture, induced pluripotent stem cell (iPSC)-derived systems, 3D cell and tissue models, and complex in vitro platforms. Responsibilities include culturing and characterizing advanced cellular models, designing and executing model development and qualification studies, establishing functional and phenotypic assays, analyzing and interpreting complex datasets, and maintaining rigorous, high-quality documentation.
The Scientist...
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