Genentech discovers, develops, manufactures and commercializes treatments for patients with serious and life-threatening medical conditions. Backed by North Carolina Biotechnology Center.
About the role
You will independently execute and optimize the synthesis of targeted and non-targeted lipid nanoparticles (LNPs) encapsulating nucleic acids for in vitro and in vivo studies. You will lead DoE-based screening campaigns directed toward discovering LNPs, setting LNP composition specifications, and optimizing LNP formulations.. Found on 1752vc Careers, the job board for startup and VC roles.
What they're looking for
- You have 2 or more years of hands-on laboratory experience specializing in LNP formulation and encapsulation of nucleic acids (mRNA, siRNA, or DNA) for in vitro and in vivo studies
- You have are highly proficient with standard LNP characterization methods, including Dynamic Light Scattering (DLS), Zeta potential, and Ribogreen assays
- You have a demonstrated level of expertise in MS Excel, hands-on experience with statistical and data analysis software (e.g., JMP, Prism)
- You have a demonstrated level experience in the LNP field in the form of publications and/or patent filings
More about this role
We are seeking a motivated and detail-oriented Scientist 3 to join our Formulation team. In this hands-on laboratory role, you will independently execute and optimize the synthesis of targeted and non-targeted lipid nanoparticles (LNPs) for nucleic acid delivery. The successful candidate will be a collaborative team player with strong technical and data analysis skills who is ready to contribute to our non-viral delivery platform.
You will independently execute and optimize the synthesis of targeted and non-targeted lipid nanoparticles (LNPs) encapsulating nucleic acids for in vitro and in vivo studies.
You will lead DoE-based screening campaigns directed toward discovering LNPs, setting LNP composition specifications, and optimizing LNP formulations..
You will collaborate cross-functionally with internal teams (biology, analytics, chemistry, and project management) to advance programs.
You will support early-stage formulation development and downstream processing activities, including cryoprotection, scale-up, and stability studies as needed.
You will maintain detailed records documenting formulation activities and results.
You will analyze, interpret, and present experimental...
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