Are you ready to decide which AAV serotypes carry Gordian’s next therapeutics into the heart, and to help reinvent how we make AAV at scale? As a Scientist on our Vector Engineering team, you’ll work directly with senior leaders to take strategic goals and... Backed by Stanford.
About the role
Your primary mission as Scientist, Vector Engineering, is to turn open scientific questions into answers Gordian can act on. Senior leaders will bring you a strategic goal; you’ll design the path to it, from the experimental plan, controls, and readouts to the failure modes worth planning around. Then you’ll run the work, interpret the data, and make the recommendation. Within your first two months, you’ll launch and lead a serotype screen for our new heart project. Found on 1752vc Careers, the job board for startup and VC roles.
More about this role
Your primary mission as Scientist, Vector Engineering, is to turn open scientific questions into answers Gordian can act on. Senior leaders will bring you a strategic goal; you’ll design the path to it, from the experimental plan, controls, and readouts to the failure modes worth planning around. Then you’ll run the work, interpret the data, and make the recommendation. Within your first two months, you’ll launch and lead a serotype screen for our new heart project. By six months, you’ll own an independent project within the team’s push to move key serotypes into suspension production, part of a goal to make more than 25% of the team’s AAV production suspension-based by Q2 2027.
You’ll also help drive the engine behind it all: the AAV production that every Gordian program depends on. Rather than handing experiments off, you’ll run them yourself, across adherent and suspension AAV production (HEK293 culture, transfections, and harvests), purification by iodixanol ultracentrifugation and FPLC. That hands-on command is what lets you troubleshoot fast, see where a method could be better, and turn that insight into your next project. You’ll calculate AAV requirements for programs, own...
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