Kymera is inventing a new generation of small molecule medicines by tackling the root cause of disease with targeted protein degradation. Backed by Bessemer.
About the role
Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics.
What they're looking for
- PhD or PharmD (or equivalent) in pharmaceutical sciences, DMPK, pharmacokinetics, chemical/biomedical engineering, or a related field, with 7+ years of hands-on PBPK/PBBM experience
- Deep understanding of ADME/DMPK and biopharmaceutics principles
- Significant hands-on GastroPlus experience (required), with a demonstrated ability to manage and deliver modeling work independently
- Experience modeling oral molecules with challenging developability profiles, including poorly soluble and/or permeable compounds and beyond-rule-of-five modalities such as targeted protein degraders (preferred)
- Proficiency in scripting for data handling, workflow automation, and model QC (e.g., R, Python, or MATLAB)
- Simcyp modeling experience (preferred)
More about this role
Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Founded in 2016, Kymera has been recognized as one of Boston’s top workplaces for the past several years. For more information about our science, pipeline and people, please visit www.kymeratx.com or follow us on X (formerly Twitter) or LinkedIn .
- PIONEER : We are courageous, resilient and rigorous in our mission to improve patients’ lives through our revolutionary degrader medicines.
- COLLABORATE : We value trust + transparency from everyone. Our goals are shared, our decisions data-driven and our camaraderie genuine.
- BELONG : We recognize our differences, inviting...
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