Kymera is inventing a new generation of small molecule medicines by tackling the root cause of disease with targeted protein degradation. Backed by Bessemer.
About the role
The Global Safety Officer (GSO) serves as the core medical safety expert and strategic safety lead for one or more assigned Kymera development programs across their full lifecycle - from early clinical development through regulatory submission and, as applicable, post-marketing surveillance.
What they're looking for
- M.D. (or equivalent international medical degree)
- Working knowledge of global PV regulations and safety reporting requirements, including FDA, EMA, and ICH E2 guidelines (E2A, E2B, E2C, E2E, E2F)
- Hands-on experience with signal detection methodology, aggregate safety reporting (DSUR, PBRER/PSUR), and development/maintenance of risk management plans (RMPs)
- Demonstrated experience authoring or substantively contributing to safety sections of regulatory submissions (IND/CTA, IB, NDA/BLA/MAA components)
- Direct experience serving as a medical safety reviewer for individual case safety reports (ICSRs) and making expedited reporting determinations
- Demonstrated ability to synthesize complex clinical and safety data into clear, actionable benefit-risk assessments
More about this role
Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Founded in 2016, Kymera has been recognized as one of Boston’s top workplaces for the past several years. For more information about our science, pipeline and people, please visit www.kymeratx.com or follow us on X (formerly Twitter) or LinkedIn .
- PIONEER : We are courageous, resilient and rigorous in our mission to improve patients’ lives through our revolutionary degrader medicines.
- COLLABORATE : We value trust + transparency from everyone. Our goals are shared, our decisions data-driven and our camaraderie genuine.
- BELONG : We recognize our differences, inviting...
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