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Scientist, mRNA Analytical Development

NewLimit · South San Francisco · On-site

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About NewLimit

NewLimit is extending human healthspan by unlocking regenerative potential. Backed by Kleiner Perkins.

About the role

We are seeking a Scientist to establish and grow NewLimit's mRNA analytical testing suite. In this role, you will lead the development of analytical methods to characterize our DNA templates and mRNAs. The assays you build will drive mRNA process development efforts as our programs advance toward the clinic. Found on 1752vc Careers, the job board for startup and VC roles.

What they're looking for

  • Experience with assay development and qualification across a broad range of mRNA analytical methods
  • Hands-on experience executing and troubleshooting HPLC separations (e.g., IP-RP-HPLC, SEC), capillary electrophoresis, and plate based assays for impurity quantification (e.g. qPCR, ELISA)
  • Ability to independently design, execute, and troubleshoot experiments
  • Ability to analyze and present complex data sets
  • Strong technical writing skills
  • Excellent communication and organizational skills
More about this role

NewLimit is a biotechnology company working to radically extend human healthspan. We’re developing medicines to treat age-related diseases by reprogramming the epigenome, a new therapeutic mechanism to restore regenerative potential in aged and diseased cells. We leverage functional genomics, pooled perturbation screening, and machine learning models to unravel the biology of epigenetic aging and disease using experiments of unprecedented scale.

We are seeking a Scientist to establish and grow NewLimit's mRNA analytical testing suite. In this role, you will lead the development of analytical methods to characterize our DNA templates and mRNAs. The assays you build will drive mRNA process development efforts as our programs advance toward the clinic.

This is a hands-on, lab-based role within Technical Operations that will interface with Delivery Sciences, research teams, and external CDMOs. It is ideal for an analytical scientist who enjoys building from the ground up and wants to expand their scope.

  • Develop and establish analytical methods for DNA template and mRNA drug substance release and characterization
  • Lead studies to evaluate method robustness, specificity, sensitivity,...

Read the full posting on NewLimit's site ↗

Technical Operations

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