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Scientist, mRNA Downstream Purification

NewLimit · South San Francisco · On-site

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About NewLimit

NewLimit is extending human healthspan by unlocking regenerative potential. Backed by Kleiner Perkins.

About the role

We are seeking a Scientist to lead downstream process development for the mRNA Engineering team. In this role, you will design, optimize, and scale purification processes for mRNA drug substance. Found on 1752vc Careers, the job board for startup and VC roles.

What they're looking for

  • Hands-on experience developing downstream purification processes for nucleic acids or other biologics
  • Hands-on experience with tangential flow filtration (TFF)
  • Experience operating ÄKTA chromatography systems
  • Ability to independently design, execute, and troubleshoot experiments
  • Ability to analyze and present complex data sets
  • Strong technical writing skills
More about this role

NewLimit is a biotechnology company working to radically extend human healthspan. We’re developing medicines to treat age-related diseases by reprogramming the epigenome, a new therapeutic mechanism to restore regenerative potential in aged and diseased cells. We leverage functional genomics, pooled perturbation screening, and machine learning models to unravel the biology of epigenetic aging and disease using experiments of unprecedented scale.

We are seeking a Scientist to lead downstream process development for the mRNA Engineering team. In this role, you will design, optimize, and scale purification processes for mRNA drug substance.

This is a hands-on, lab-based role that spans program process development and platform engineering. It is ideal for a scientist who enjoys solving purification challenges and scaling processes in a dynamic, fast-paced environment.

  • Design, execute, and analyze process development studies for mRNA purification
  • Act as the downstream lead for CMC program teams
  • Help design and implement automated downstream workflows for high-throughput purification of research-grade mRNA
  • Support execution of research-grade mRNA production runs for discovery...

Read the full posting on NewLimit's site ↗

Technical Operations

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