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About the role
We are seeking a talented and highly motivated individual with a strong background in synthetic organic chemistry to join our medicinal chemistry group in the pursuit of degrader-based small molecules to treat patients with unmet medical needs. This individual will design and synthesize novel chemical entities optimized for potency, selectivity, pharmacokinetics and in vivo efficacy, and will engage in rational structure-based drug discovery enabled by our computational and structural biology groups. Found on 1752vc Careers, the job board for startup and VC roles.
What they're looking for
- Ph.D. in synthetic organic chemistry with 8 – 10+ years pharmaceutical medicinal chemistry industrial experience
- Track record of delivering advanced leads/ development candidates
- Expert in organic synthesis, knowledgeable of the current literature, with strong synthetic problem-solving skills
- Proven leadership capability in a cross-functional team setting, either as project team leader or co-lead
- Ability to make inventive contributions towards new chemical target structures or templates for programs and evaluate early screening or literature hits
- Strong skills in gathering, documenting, and analyzing information from competitive sources such as patents and meetings and using this information to guide program strategy
More about this role
Senior/Principal Scientist, Medicinal Chemistry
About the Position
We are seeking a talented and highly motivated individual with a strong background in synthetic organic chemistry to join our medicinal chemistry group in the pursuit of degrader-based small molecules to treat patients with unmet medical needs. This individual will design and synthesize novel chemical entities optimized for potency, selectivity, pharmacokinetics and in vivo efficacy, and will engage in rational structure-based drug discovery enabled by our computational and structural biology groups. As a member of a dynamic multi-disciplinary team, this person will collaborate with a broad group of scientists within Nurix and with external collaborators. Additionally, they will contribute to patent, report and scientific publication writing. Furthermore, they will initiate and/or lead process improvements within the chemistry department or cross-functionally.
Qualifications
- Ph.D. in synthetic organic chemistry with 8 – 10+ years pharmaceutical medicinal chemistry industrial experience.
- Track record of delivering advanced leads/ development candidates.
- Excellent knowledge of medicinal chemistry principles...
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