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About the role
Help move Nurix’s portfolio from the bench to the clinic. As a Senior Scientist in Chemical Development, you’ll scout routes, build scalable processes, and work with CROs/CDMOs to supply drug substance for early clinical trials, spending up to half your time hands-on in the lab. It’s a role with broad responsibilities and real opportunity in a small, entrepreneurial environment. Found on 1752vc Careers, the job board for startup and VC roles.
What they're looking for
- Route scouting of pre-clinical and clinical candidates
- Support the pre-clinical research team by developing robust and scalable processes to support initial scale-up for animal studies
- Work up to 50% of the time in the lab to support early route scouting and discovery scale-up efforts toward CMC transition
- Author tech transfer documents and work with CROs/CDMOs to effectively and efficiently reproduce chemistry at various sites
- Support RSM and DS manufacturing activities at CRO/CDMO sites, including scale-up of candidate compounds to support candidate selection during drug discovery
- Prepare and/or review CMC sections of INDs, CTAs, NDAs, MAAs and other regulatory submissions
More about this role
Help move Nurix’s portfolio from the bench to the clinic. As a Senior Scientist in Chemical Development, you’ll scout routes, build scalable processes, and work with CROs/CDMOs to supply drug substance for early clinical trials, spending up to half your time hands-on in the lab. It’s a role with broad responsibilities and real opportunity in a small, entrepreneurial environment.
- Own chemical development activities across the portfolio, including process development and manufacture of regulatory starting materials (RSMs) and supporting production of Drug Substance (DS) for clinical trial materials, with a focus on the early development space
- Route scouting of pre-clinical and clinical candidates
- Support the pre-clinical research team by developing robust and scalable processes to support initial scale-up for animal studies
- Work up to 50% of the time in the lab to support early route scouting and discovery scale-up efforts toward CMC transition
- Author tech transfer documents and work with CROs/CDMOs to effectively and efficiently reproduce chemistry at various sites
- Support RSM and DS manufacturing activities at CRO/CDMO sites, including scale-up of candidate compounds...
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