AI agents that run your enterprise workflows and get measurably better over time. 150+ enterprises live in production across retail, insurance, and financial services. Backed by Accel and General Catalyst.
About the role
Drive medicinal chemistry strategy for Nurix's discovery programs, from hit optimization through development candidate nomination. You'll design novel compounds, interpret complex SAR across multidisciplinary datasets, and help set new scientific directions, with opportunities to lead chemistry workstreams and mentor colleagues. Found on 1752vc Careers, the job board for startup and VC roles.
What they're looking for
- Design novel chemical entities and medicinal chemistry strategies, applying structure-based drug design to optimize potency, selectivity, physicochemical properties, ADME/PK, safety, and in vivo efficacy
- Design synthetic strategies for complex molecules using modern and creative synthetic methods
- Partner closely with computational chemists, structural biologists, and colleagues across biology, pharmacology, and DMPK to advance project objectives
- Develop innovative concepts that establish new directions and address complex challenges, drawing on emerging literature, patents, and competitive intelligence to inform compound design and strategy
- Lead chemistry workstreams within multidisciplinary teams, independently manage priorities and external collaborations, and contribute to project strategy and key scientific decisions
- Provide scientific guidance, coaching, and mentorship to other scientists
More about this role
Drive medicinal chemistry strategy for Nurix's discovery programs, from hit optimization through development candidate nomination. You'll design novel compounds, interpret complex SAR across multidisciplinary datasets, and help set new scientific directions, with opportunities to lead chemistry workstreams and mentor colleagues.
- Design novel chemical entities and medicinal chemistry strategies, applying structure-based drug design to optimize potency, selectivity, physicochemical properties, ADME/PK, safety, and in vivo efficacy
- Design synthetic strategies for complex molecules using modern and creative synthetic methods
- Develop and interpret SAR by integrating chemical, structural, computational, biochemical, cellular, pharmacological, and ADME/PK data; independently identify key questions, design experiments, and recommend compound or series advancement, redesign, or termination
- Partner closely with computational chemists, structural biologists, and colleagues across biology, pharmacology, and DMPK to advance project objectives
- Develop innovative concepts that establish new directions and address complex challenges, drawing on emerging literature, patents, and...
Browse similar: AI jobs · AI startup jobs · Startup jobs