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About the role
Help shape Nurix’s induced proximity strategy beyond targeted protein degradation. In this hands-on role, you’ll design and run the assays that validate targets, characterize mechanisms and inform go/no-go decisions, working alongside chemistry, biology and biochemistry partners. It’s a chance to grow your scientific, and potentially leadership, experience in a fast-evolving area of drug discovery with direct exposure to platform-level strategy. Found on 1752vc Careers, the job board for startup and VC roles.
What they're looking for
- Design, execute, and troubleshoot experiments at the bench, building and running biochemical, biophysical, and cell-based assays to interrogate induced proximity mechanisms and drive program decisions
- Contribute to identification, validation, and prioritization of targets amenable to induced proximity approaches (protein sequestration, gene regulation, stabilizers, and related mechanisms)
- Evaluate and integrate new and emerging induced proximity modalities into the strategic roadmap
- Partner with computational/structural biology to advance rational design and predictive modeling of ternary complex formation
- Present experimental data, interpretations, and recommendations to project teams and executive leadership
- Ensure programs meet key milestones from discovery through candidate nomination and IND-enabling work
More about this role
Help shape Nurix’s induced proximity strategy beyond targeted protein degradation. In this hands-on role, you’ll design and run the assays that validate targets, characterize mechanisms and inform go/no-go decisions, working alongside chemistry, biology and biochemistry partners. It’s a chance to grow your scientific, and potentially leadership, experience in a fast-evolving area of drug discovery with direct exposure to platform-level strategy.
- Nurix Therapeutics, Inc. is seeking a motivated scientist to support and help execute the non-degradative induced proximity research strategy. This individual will contribute hands-on scientific expertise to programs beyond targeted protein degradation, helping advance target validation, mechanism characterization, and candidate optimization efforts. Working closely with the Senior Vice President of Induced Proximity and cross-functional partners in chemistry, biology, and biochemistry, this person will help translate strategic priorities into experimental plans, generate and interpret data that inform go/no-go decisions, and contribute ideas on emerging modalities and technologies worth exploring. This is an opportunity to grow...
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