Repertoire Immune Medicines is a clinical-stage biotechnology company working to unlock and direct the remarkable power of the human immune system to prevent or treat cancer, as well as autoimmune and infectious disease. Backed by SoftBank VF.
About the role
We are seeking an experienced Clinical Trial Manager to provide both strategic leadership and hands-on oversight of early-stage oncology trials, including first-in-human trials. Reporting to the Director of Clinical Operations, you will oversee all aspects of trial management -from start-up through close-out - ensuring trials are delivered on time, on budget, and fully compliant with regulatory and quality standards.
What they're looking for
- Work with a cross-functional trial teams to manage all aspects of clinical trials ensuring trials are executed on time, on budget, and in compliance with SOPs, ICH/GCP, and regulatory requirements
- Identify and anticipate trial issues or risks that may impact budget, resources, and timelines, plan mitigation strategies with the cross-functional team and escalates as necessary
- Manage trial budgets and contracts, including forecasting, invoice review, and expense tracking for accurate reporting
- Monitor trial progress, including participant enrollment, clinical data review, sample collection, and adherence to timelines, provide regular trial status updates and metrics
- Guide trial teams and investigator sites to ensure consistent interpretation and execution of trial protocols and procedures
- Contribute to the development and review of trial-related documents (protocols, ICFs, clinical trial plans, CRFs, manuals, reports, and regulatory documentation)
More about this role
Company Overview
Repertoire Immune Medicines is a clinical-stage biotechnology company harnessing the power of the human immune system to develop transformative therapies for cancer and autoimmune disease. Using its proprietary DECODE™ platform—which maps the immune synapse between T cell receptors (TCRs) and their antigen targets—Repertoire translates unique biological insights into potent and targeted off-the shelf immune medicines. The company integrates deep protein engineering expertise with artificial intelligence, powered by a proprietary DECODE database of over one billion TCR-antigen interactions, to accelerate discovery and optimize drug candidates.
From its sites in Cambridge, Massachusetts and Zurich, Switzerland, Repertoire is advancing a pipeline of T cell-targeted immunotherapies with the potential to address a broad range of cancers and autoimmune disorders. The company’s lead oncology program, RPTR-1-201, a TCR bispecific, has initiated a Phase 1/2 clinical trial across multiple solid tumor indications. Repertoire plans to advance additional TCR bispecific therapies into clinical trials over the next 12-18 months. In autoimmune disease, Repertoire is partnering...
Read the full posting on Repertoire Immune Medicines's site ↗
Browse similar: Startup jobs · Remote jobs