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Senior Bioinformatics Engineer, Infrastructure

Repertoire Immune Medicines · Remote (US) · Remote

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About Repertoire Immune Medicines

Repertoire Immune Medicines is a clinical-stage biotechnology company working to unlock and direct the remarkable power of the human immune system to prevent or treat cancer, as well as autoimmune and infectious disease. Backed by SoftBank VF.

About the role

Repertoire Immune Medicines is seeking a Senior Bioinformatics Engineer to join our Computational Engineering team and help power the discovery of transformational immune medicines from our growing immune synapse database. As one of a small group of high-impact engineers, you will make extensive proprietary datasets discoverable, trustworthy, and ready for internal analysis at scale. Found on 1752vc Careers, the job board for startup and VC roles.

What they're looking for

  • Build and operate bioinformatics pipelines from instrument to data ecosystem using workflow orchestration and containerized execution
  • Build durable data platforms that support data discovery by exposing data through clean, well-documented internal APIs, applications, and SQL databases
  • Provision and manage cloud infrastructure as code with secure engineering practices that keep systems robust, safe, and maintainable
  • Own engineering standards for the team including CI/CD test automation, version control, and design and review practices that keep systems maintainable as the team grows
  • Lead incident reviews and preventative improvements to diagnose the root cause of failures and build safeguards that prevent recurrence with verifiable gating mechanisms
  • Own end-to-end data processing and delivery to support scientific decision making around the organization
More about this role

Repertoire Immune Medicines is a clinical-stage biotechnology company harnessing the power of the human immune system to develop transformative therapies for cancer and autoimmune disease. Using its proprietary DECODE TM platform—which maps the immune synapse between T cell receptors (TCRs) and their antigen targets—Repertoire translates unique biological insights into potent and targeted off-the shelf immune medicines. The company integrates deep protein engineering expertise with artificial intelligence, powered by a proprietary DECODE database of over one billion TCR-antigen interactions, to accelerate discovery and optimize drug candidates.

From its sites in Watertown, Massachusetts and Zurich, Switzerland, Repertoire is advancing a pipeline of T cell-targeted immunotherapies with the potential to address a broad range of cancers and autoimmune disorders. The company’s lead oncology program, RPTR-1-201, a TCR bispecific, has initiated a Phase 1/2 clinical trial across multiple solid tumor indications. Repertoire plans to advance additional TCR bispecific therapies into clinical trials over the next 12-18 months. In autoimmune disease, Repertoire is partnering with leading...

Read the full posting on Repertoire Immune Medicines's site ↗

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