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Executive Director, Portfolio Systems & Strategy Integration

Revolution Medicines · Redwood City, California, United States · On-site

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About Revolution Medicines

Backed by GV.

About the role

This is a unique and high-impact opportunity to help shape how a rapidly growing oncology company manages its pipeline, prioritizes decisions, and integrates strategic intelligence across its portfolio. Revolution Medicines is at an inflection point — with a growing clinical pipeline, increasing organizational complexity, and significant decisions ahead around program advancement, resource allocation, and competitive positioning. This role sits at the center of that work. Found on 1752vc Careers, the job board for startup and VC roles.

What they're looking for

  • 10+ years of experience in portfolio management, strategy, or a related function within a biotechnology or pharmaceutical company, with increasing scope and responsibility
  • Direct experience with portfolio governance, including support of portfolio review committees, decision tracking, and cross-functional coordination at the program level
  • Strong systems thinking and data fluency — ability to design or improve portfolio tracking tools and dashboards, work with structured data, and translate complex information into clear, decision-ready outputs
  • Demonstrated ability to manage complex, multi-stakeholder projects with minimal supervision, balancing rigor with pragmatism and speed
  • Excellent communication and executive presence — ability to prepare and present materials for senior leadership, simplify complex topics, and build credibility quickly with a broad range of stakeholders
  • High degree of operational savvy and organizational awareness — understands how things get done in a matrixed organization and knows how to navigate ambiguity and competing priorities
More about this role

Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.

Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients.

This is a unique and high-impact opportunity to help shape how a rapidly growing oncology company manages its pipeline, prioritizes decisions, and integrates strategic intelligence across its portfolio. Revolution Medicines is at an inflection point — with a growing clinical pipeline, increasing organizational complexity, and significant decisions ahead around program advancement, resource...

Read the full posting on Revolution Medicines's site ↗

Program, Lifecycle and Portfolio...

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