Backed by Norwest and a16z.
About the role
Located in San Francisco’s vibrant Mission Bay neighborhood, Rezo is in close proximity to UCSF, numerous urban amenities, and outdoor recreational opportunities. We recognize that realizing our mission depends as much on our people as it does on our science and are building a workplace that fosters collaboration, respect, and diversity where contributing to your team’s success is valued as highly as individual achievements. Found on 1752vc Careers, the job board for startup and VC roles.
What they're looking for
- Own chemistry strategy and execution across the small-molecule portfolio, with particular focus on late-stage lead optimization, candidate quality, developability, and clear nomination criteria
- Drive rigorous development candidate selection, including definition of backup strategies and assessment of route scalability, formulation feasibility, and intellectual property
- Lead the CMC strategy for nominated candidates through IND-enabling studies and first-in-human readiness, spanning drug substance, drug product, analytical development, and phase-appropriate control strategies
- Provide accountable oversight of CROs and CDMOs: partner selection, scopes of work, technical decisions, budgets, quality, risk mitigation, technology transfer, and milestone delivery
- Build, mentor, and develop a high-performing internal chemistry organization while leveraging external capabilities, establish a culture of scientific rigor, transparent decision-making, urgency, and accountability
- Collaborate closely with biology, structural biology, computational sciences, pharmacology, and leadership to integrate emerging data and make disciplined portfolio decisions
More about this role
About Rezo Therapeutics
Rezo is a different kind of biopharma company. Our mission is to dramatically increase the success rate of drug development by building a disease-agnostic, fully-integrated, network biology platform that will redefine our understanding of human disease and ability to treat it.
We are leveraging a unique integrated approach, combining capabilities in genetics, proteomics, structural biology and AI to generate deep biological insights and novel therapeutic approaches.
Located in San Francisco’s vibrant Mission Bay neighborhood, Rezo is in close proximity to UCSF, numerous urban amenities, and outdoor recreational opportunities. We recognize that realizing our mission depends as much on our people as it does on our science and are building a workplace that fosters collaboration, respect, and diversity where contributing to your team’s success is valued as highly as individual achievements. If you’re passionate about team science and breaking down barriers to progress in drug development, please consider joining us!
The Opportunity
Rezo Therapeutics is advancing a new approach to small-molecule drug discovery focused on targeting disease-relevant protein...
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