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Senior HPC & GPU Infrastructure Engineer

Sciforium · San Francisco, CA · On-site

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About Sciforium

Sciforium builds the next generation of AI models with unprecedented efficiency, privacy, and versatility. Backed by SignalFire.

About the role

We are seeking a Senior HPC & GPU Infrastructure Engineer to take full ownership of the health, reliability, and performance of our GPU compute cluster. You will be the primary custodian of our high-density accelerator environment and the linchpin between hardware operations, distributed systems, and machine learning workflows. This role spans everything from hands-on Linux systems engineering and GPU driver bring-up to maintaining the ML software stack (CUDA/ROCm, PyTorch, JAX, vLLM). Found on 1752vc Careers, the job board for startup and VC roles.

What they're looking for

  • 5+ years of experience in HPC, GPU cluster operations, Linux systems engineering, or similar roles
  • Bachelor’s or Master’s degree in Computer Science, Computer Engineering, Electrical Engineering, or a related technical field
  • Strong expertise with NVIDIA (H100/B200) or AMD (MI325x/MI355x) GPUs, including driver and kernel-level debugging
  • Deep understanding of Linux internals, kernel modules, hardware bring-up, and systems performance tuning
  • Experience with network security, including VPNs, iptables/firewalld, SSH, and identity management (LDAP/FreeIPA/AD)
  • Proficiency in Bash and Python for scripting, automation, and workflow tooling
More about this role

Sciforium is an AI infrastructure company developing next-generation multimodal AI models and a proprietary, high-efficiency serving platform. Backed by multi-million-dollar funding and direct sponsorship from AMD with hands-on support from AMD engineers the team is scaling rapidly to build the full stack powering frontier AI models and real-time applications.

We are seeking a Senior HPC & GPU Infrastructure Engineer to take full ownership of the health, reliability, and performance of our GPU compute cluster. You will be the primary custodian of our high-density accelerator environment and the linchpin between hardware operations, distributed systems, and machine learning workflows. This role spans everything from hands-on Linux systems engineering and GPU driver bring-up to maintaining the ML software stack (CUDA/ROCm, PyTorch, JAX, vLLM). If you love squeezing every bit of performance out of hardware, enjoy debugging GPUs at scale, and want to build world-class AI infrastructure, this role is for you.

1. System Health & Reliability (SRE)

On-Call Response: Act as the primary responder for system outages, GPU failures, node crashes, and cluster-wide incidents. Minimize downtime...

Read the full posting on Sciforium's site ↗

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