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Senior Associate Bioengineer/Bioengineer, Automation & Systems Testing.

Spear Bio · Woburn, MA Headquarters · On-site

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About Spear Bio

Backed by Foresite Capital.

About the role

We are seeking a motivated Sr. Associate Bioengineer / Bioengineer, Systems Integration to work at the intersection of immunoassay biology, engineering systems, and automated workflows on Spear Bio’s SPEAR S.W.I.F.T. platform. This is a broad, hands-on integration role —not narrowly scoped to testing alone. Found on 1752vc Careers, the job board for startup and VC roles.

What they're looking for

  • Master’s or Ph.D. in Biomedical Engineering, Bioengineering, Chemical Engineering, Systems Engineering, Mechanical/Electrical Engineering, or a related field. Exceptional Bachelor’s candidates with strong industry experience will be considered
  • Demonstrated track record of independently driving technical work—not just executing protocols defined by others
  • Strong foundation in both biological assay workflows (proteomic immunoassays, qPCR/nucleic acid amplification) and engineering subsystems (liquid handling, thermal, optics, mechatronics)
  • Hands-on experience with automated platforms (Hamilton, Tecan, Formulatrix, Roche, Bio-Rad, or similar). Prior experience with FAST-type liquid handlers and/or qPCR instruments is strongly preferred
  • Programming/scripting proficiency (Python required, C#, MATLAB, or similar a plus) for automation, data analysis, and pipeline development
  • Experience with experiment design (DOE), statistical analysis (SPC, Gage R&R), and data visualization
More about this role

Spear Bio, founded in 2021, is a well-funded and rapidly growing biotech start-up headquartered in Woburn, Massachusetts. Our proprietary technology, Successive Proximity Extension Amplification Reaction (SPEAR) , is a novel wash-free immunoassay platform, offering unprecedented sensitivity. We are dedicated to revolutionizing early disease diagnosis and monitoring by providing scalable, ultrasensitive solutions that deliver unparalleled accuracy in measuring low-abundant biomarkers, enabling clinicians and researchers to improve patient outcomes and advance global health.

We are seeking a motivated Sr. Associate Bioengineer / Bioengineer, Systems Integration to work at the intersection of immunoassay biology, engineering systems, and automated workflows on Spear Bio’s SPEAR S.W.I.F.T. platform. This is a broad, hands-on integration role —not narrowly scoped to testing alone. You will design and execute experiments, integrate and troubleshoot complex subsystems, interpret assay and instrument data, develop and automate workflows, and build the validation evidence that ensures our platforms deliver reliable, reproducible results.

This role carries a clear growth trajectory toward...

Read the full posting on Spear Bio's site ↗

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