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Scientist/Senior Scientist, High-Throughput Screening

until · Bay Area · On-site

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About until

Until is building a pause button for biology, so every single transplantable organ finds a recipient and saves a life. Backed by Founders Fund and Lux.

About the role

We are seeking a Scientist/Senior Scientist, High-Throughput Screening to manage the day-to-day execution of our cryoprotectant screening program. You will be responsible for improving an established screening workflow, increasing throughput, identifying less-toxic formulations, and advancing our understanding of how cryoprotectants affect cell viability and function. Found on 1752vc Careers, the job board for startup and VC roles.

What they're looking for

  • Experienced in independently designing, executing, and improving cell-based high-throughput screening workflows
  • Skilled in assay development using primary cells or iPSC-derived cells, with experience in at least one renal, cardiac, or hepatic model
  • Experienced in developing mechanistic assays and translating screening results into testable hypotheses about cellular toxicity
  • Comfortable working hands-on with plate-based assays, imaging, flow cytometry, and analytical chemistry methods such as HPLC, LC-MS, or GC-MS for compound purity assessment
  • Experienced in quantitative analysis of screening data, including quality control, statistical interpretation, and analysis of multiple experimental readouts
  • Able to coordinate and mentor a scientific team, manage interdependent workflows, and take responsibility for experimental execution and outcomes
More about this role

Until is a moonshot company building a “pause button” for biology. Our near-term focus is organ-scale reversible cryopreservation: preserving donated organs at subzero temperatures without ice formation, then rewarming them uniformly for transplant. By solving this grand challenge, we’re laying the foundation for whole-body reversible cryopreservation, giving patients a bridge to future cures.

To achieve our goal, we are assembling an interdisciplinary team to develop perfusion systems, cryoprotectant formulations, and vitrification and rewarming hardware.

We envision a future where no transplantable organ is lost to logistics, and no terminal diagnosis is final because patients can safely wait for future medicine to arrive.

We are seeking a Scientist/Senior Scientist, High-Throughput Screening to manage the day-to-day execution of our cryoprotectant screening program. You will be responsible for improving an established screening workflow, increasing throughput, identifying less-toxic formulations, and advancing our understanding of how cryoprotectants affect cell viability and function.

Working closely with assay scientists, biologists, and automation engineers, you will...

Read the full posting on until's site ↗

Molecular Development

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